From Emulsion to Single-phase Microfluidics: an Integrated Approach to Culture and Perfusion of Multicellular Spheroids
نویسندگان
چکیده
This study presents a novel microfluidic approach for developing large scale screening assays of anticancer compounds on 3D multicellular spheroids. We have developed a microfluidic device with associated protocols that combine the high-throughput characteristics of droplet microfluidics for spheroid formation and aggregation with those of single-phase microfluidics for substance exchange, long term culture and drug perfusion.
منابع مشابه
Transitioning from multi-phase to single-phase microfluidics for long-term culture and treatment of multicellular spheroids.
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